Several factors can increase the risk of gastrointestinal hemorrhage, including the use of nonsteroidal anti-inflammatory drugs (NSAIDs), anticoagulants, and a history of peptic ulcer disease. Other contributing factors include chronic liver disease, diverticulosis, and inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. Additionally, age, excessive alcohol consumption, and certain infections may further elevate the likelihood of experiencing gastrointestinal bleeding.