Infective arthritis, also known as septic arthritis, is primarily caused by the invasion of infectious agents such as bacteria, viruses, or fungi into a joint. The most common causative organism is Staphylococcus aureus, but other pathogens, including Streptococcus species and Neisseria gonorrhoeae, can also be responsible, particularly in sexually active adults. Risk factors for developing infective arthritis include existing joint conditions, recent joint injections, diabetes, immunosuppressive conditions, and intravenous drug use, which can increase susceptibility to infections.