Spondylopathies, including spondyloarthropathy, encompass a group of inflammatory diseases that primarily affect the spine and sacroiliac joints. These conditions can arise from a combination of genetic factors, such as the presence of HLA-B27 antigen, and environmental triggers, including infections that may provoke an autoimmune response. In the case of infective spondylitis, bacteria or other pathogens can directly invade the vertebral structures, leading to inflammation and pain.